Decorative Curve

The MOSAIC dataset

Large-scale spatial omics data fuels cancer research

Demonstrating MOSAIC Window
The convergence of large-scale spatial omics data and AI will power the next revolution of oncology research.

There is an urgent need for the whole cancer community to have access to these data to reveal groups of patients with distinct tumour/immune biology.

MOSAIC will overcome this limitation by creating a large scale dataset of tumor spatial transcriptomes, allowing scientists to conduct research on data from cohorts larger than what is currently possible.

The MOSAIC dataset today

6
Data modalities
More information
11
Therapy areas
More information
100
Clinical variables per patient
2,725
Total patients included
2,371
Spatial omics data generated
2,168
Single-cell omics generated

Data modalities and cancer therapy areas

MOSAIC captures the complexity of disease biology across six data modalities and selected cohorts spanning ten cancer indications. Here is a breakdown of the current number of patient samples across each modality and therapy area in the dataset.

Clinical
Bulk RNA seq
2114
Single Cell RNA Seq
2168
Whole Exome
2266
Spatial Transcriptomics
2371
H&E WSI
2666
Bladder Cancer
265
patients represented
Clinical
H&E WSI
Whole Exome
Spatial Transcriptomics
Bulk RNA seq
Single Cell RNA Seq
EU
Breast Cancer
206
patients represented
Clinical
H&E WSI
Whole Exome
Spatial Transcriptomics
Bulk RNA seq
Single Cell RNA Seq
EU
Colorectal Cancer
66
patients represented
Clinical
H&E WSI
Whole Exome
Spatial Transcriptomics
Bulk RNA seq
Single Cell RNA Seq
EU
Diffuse large B-cell lymphoma
375
patients represented
Clinical
H&E WSI
Whole Exome
Spatial Transcriptomics
Bulk RNA seq
Single Cell RNA Seq
EU NA
Gastric Cancer
17
patients represented
Clinical
H&E WSI
Single Cell RNA Seq
EU
Glioblastoma
282
patients represented
Clinical
H&E WSI
Whole Exome
Spatial Transcriptomics
Bulk RNA seq
Single Cell RNA Seq
EU
Head & Neck Squamous Cell Carcinoma
118
patients represented
Clinical
H&E WSI
Whole Exome
Spatial Transcriptomics
Bulk RNA seq
Single Cell RNA Seq
EU
Mesothelioma
86
patients represented
Clinical
H&E WSI
Whole Exome
Spatial Transcriptomics
Bulk RNA seq
Single Cell RNA Seq
EU
Non-small cell lung cancer
368
patients represented
Clinical
H&E WSI
Whole Exome
Spatial Transcriptomics
Bulk RNA seq
Single Cell RNA Seq
EU
Ovarian cancer
334
patients represented
Clinical
H&E WSI
Whole Exome
Spatial Transcriptomics
Bulk RNA seq
Single Cell RNA Seq
EU
Pancreatic Cancer
131
patients represented
Clinical
H&E WSI
Whole Exome
Spatial Transcriptomics
Bulk RNA seq
Single Cell RNA Seq
EU

How to access the MOSAIC dataset

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Option 1 - Access via the EGA

MOSAIC Window, a subset of the MOSAIC dataset, is available via the European Genome-Phenome Archive (EGA).

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Option 2 - Explore via K Pro

Explore the MOSAIC dataset via Owkin’s AI Scientist, K Pro.

K Pro is the first AI agent connecting research and care. It continuously learns from real-world data, user feedback, and clinical validation, evolving toward fully automated R&D.