News
MOSAIC: Intra-tumoral heterogeneity characterization through large-scale spatial and cell-resolved multi-omics profiling
We’re proud to share our latest publication: our large-scale, multi-center initiative mapping tumor complexity across thousands of cancer patients using spatial and single-cell omics, histology, and AI.
MOSAIC integrates:
- Spatial & single-cell transcriptomics
- Bulk RNA and exome sequencing
- H&E histology
- Curated, clinically-defined cohorts
We also introduce MOSAIC Window, a publicly available subset of 60 patients released via the EGA. Using four deeply profiled patients, we demonstrate how multi-omic analysis reveals intra-tumoral variability, uncovers cancer subpopulations with distinct drug sensitivities, and informs therapeutic recommendations.
About MOSAIC
MOSAIC is a large-scale initiative that combines patient samples and technologies from multiple institutions, hospitals and technology partners, who are joining forces with Owkin to create the largest multimodal, spatial omics atlas in cancer.